What are the Health Effects Associated with Pentachlorophenol? 3 and .
The following filters may also be used: N99, R99, P99, N100, R100, P100. In its pure form, pentachlorophenol has a strong phenolic odor. The miscellaneous mill uses primarily involve the application of pentachlorophenol as a slime reducer in paper and pulp milling and may constitute 6% of the total annual consumption of pentachlorophenol (Crosby et al., 1981). PCP of 98% purity has been described as cream-colored, while technical-grade PCP is pale brown in color ( NTP, 1989 ). Properties. 5.1 Exposure data. PCP is considered a "probable human carcinogen" by the U.S. Environmental Protection Agency (EPA). Impure pentachlorophenol (the form usually found at hazardous waste sites) is dark gray to brown and exists as dust, beads, or flakes. You can smell the chemical in the water at less than 12 ppm.
When it is really hot, it has a sharp chemical smell but at room temperature there is just a very faint odor. Pentachlorophenol was widely used as a pesticide and wood preservative. Since 1984, the purchase and use of PCP have been restricted to certified applications. Pentachlorophenol can be analyzed by this reverse phase (RP) HPLC method with simple conditions. Pentachlorophenol is a manufactured organic chemical not found naturally in the environment. Under the Guidelines for Carcinogen Risk Assessment (U.S. EPA, 2005a), PCP is "likely to be carcinogenic to humans." This may be a synopsis of the full weight-of-evidence narrative. Other Long-Term Effects * Pentachlorophenol may damage the liver and kidneys. It can also cause other non-cancer health risks. (USCG, 1999) Reactivity Profile PENTACHLOROPHENOL may react with strong oxidizing agents. Pentachlorophenol is a colorless to white, sand-like solid. Though once widely used as an herbicide, it was banned in 1987 for these and other uses, as well as for any over-the-counter sales. Wood Preservatives and Pressure Treating Pentachlorophenol is a colorless to white, sand-like solid. Governments around the world will decide on the recommendation in 2015. After decades of restricting the use of pentachlorophenol, the US Environmental Protection Agency proposed a complete ban on it in early 2021. in Solvent and Volume 1000 g/mL in methanol, 1 mL/ampul Units ea. It has a pungent odor when hot and is used in making pesticides and fungicides, and as a wood preservative. Humans are usually exposed to impure pentachlorophenol (also called technical grade pentachlorophenol). CiteSeerX - Document Details (Isaac Councill, Lee Giles, Pradeep Teregowda): What is pentachlorophenol? 5. (1) The odor threshold for pentachlorophenol is approximately 12 parts per million (ppm). Pentachlorophenol (PCP) is an industrial wood preservative used mainly to treat utility poles and cross arms. Pentachlorophenol (PCP) is a restricted use pesticide that can only be used by professionals. As a wood preservative, pentachlorophenol acts as both a fungicide and insecticide (Freiter, 1978). Technical grade pentachlorophenol contains many impurities, depending on the manufacturing method used. Pentachlorophenol can enter the environment (in air, water, and soil) via evaporation from treated woods, industrial spills, and disposal at hazardous waste sites. The molecular formula of this chemical is C 6 Cl 5 OH. (1) Impure pentachlorophenol is dark gray to brown and exists as dust, beads, or flakes. The US National Toxicology Program lists pentachlorophenol as a "reasonably anticipated" human carcinogen. Bulk Method Additional Resources and Literature References NOAA: CAMEO Chemicals - Pentachlorophenol grade. Impure pentachlorophenol (the form usually found at hazardous waste sites) is dark gray to brown and exists as dust, beads, or flakes. Expired - Lifetime Application number US00066890A Inventor J Francis L Horcher Summary of Data Reported and Evaluation. certified reference material TraceCERT . Dust or vapor irritates skin and mucous membranes, causing coughing and sneezing. Pentachlorophenol does biodegrade but may require several weeks for acclimation. Its solubility in water is 0.0014 g/100 mL. Pentachlorophenol mineralization in water from several sites was very low (<5 ng/L per day). Pentachlorophenol in solution can be readily absorbed through intact skin in toxic amounts, causing systemic poisoning and symptoms described in the Inhalation section above. Pentachlorophenol: Class: Small Molecule: Description: Pentachlorophenol (PCP) is an organochlorine compound used as a pesticide and a disinfectant. All mass spectra in this site (plus many more) are available from the NIST/EPA/NIH Mass Spectral Library. During the method development, it was found that the pH of the mobile phase has an obvious influence on the retention time and peak shape of pentachlorophenol and niclosamide; when the elution strength was increased too rapidly to 90% methanol, niclosamide and fenpropathrin had similar retention times and this . Pentachlorophenol | C6Cl5OH or C6HCl5O | CID 992 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological . Pentachlorophenol exists as colorless or white crystals (when pure) with a sharp, phenolic odor when hot, but very little odor at room temperature. Pentachlorophenol (PCP) is an industrial wood preservative used mainly to treat utility poles and cross arms. PENTACHLOROPHENOL * All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details. During the registration review process, EPA found that given the emergence of viable alternatives, "the risks pentachlorophenol poses to workers' health outweigh the . This month, EPA followed through on the ban, which . adsorption of pentachlorophenol/phenate (5 mg/l) diminishes markedly at ph values above the pka of this weak acid (equal to 5.9 : 0.1) when the pentachlorophenol exists almost entirely in ionic form in aqueous solution, and is enhanced at low ph when the percentage of molecular species (whose concentration can be determined from pka value) It is used as a wood preservative for making utility poles, railroad ties, and wharf support pilings. At one time, it was one of the most widely used biocides in the United States. All personnel handling treated wood or handling treating equipment (including poles/hooks used to retrieve charge cables) that has come in contact with preservative must wear the following PPE: (1) washable or disposable coveralls or long-sleeved shirt and long pants, (2 . Ingestion causes loss of appetite, respiratory difficulties, anesthesia, sweating, coma. It has a pungent odor when hot and is used in making pesticides and fungicides, and as a wood preservative.. What is pentachlorophenol used for? The Committee justified its recommendation for the Stockholm Convention due to pentachlorophenol's persistence, bioaccumulation, long-range transport, and its toxic impacts. In an artificial stream, microbial degradation became significant after 3 weeks and accounted for 26-46% removal. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. Pentachlorophenol can be found in two forms: pentachlorophenol itself or as the . What does pentachlorophenol smell like? Pentachlorophenol can be found in two forms: pentachlorophenol itself or as the . Pentachlorophenol (PCP) is an organochlorine wood preservative used to treat utility poles in the United States. Penta is "cheap, easy, and effective," explains Philip Ford, director of technical sales and quality conformance at American Borate, which makes wood preservatives for other applications. Molecular formula C 6 HCl 5 O Formula weight 266.3 g/mol Family Phenolic compounds Properties (at room temperature where applicable) Environmental behaviour At 20 0C, pentachlorophenol is a solid with very low volatility and moderate solubility. PCP has been used as a wood preservative since 1936. NIOSH/OSHA. The EPA claims that "pentachlorophenol poses significant human health risks to workers." It is a man-made chemical that is not found naturally in the environment. PubChem Substance ID: 24864934. Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (27 pp, 261 K) Oral Slope Factor: 4 x 10 -1 per mg/kg-day.
Pentachlorophenol can be found in two different forms either as PCP or as its sodium salt. [3] It can be found as pure PCP, or as the sodium salt of PCP, the latter of which dissolves easily in water. * Pentachlorophenol may damage the developing fetus. The Pentachlorophenol, with the CAS registry number 87-86-5 and EINECS registry number 201-778-6, is also called PCP. Removal of pentachlorophenol (PCP) from wastewater containing chlorophenols, due to its toxicity, mutagenic and carcinogenic properties, has been attracted much interests of researchers. Pentachlorophenol is classified as a substance considered to be carcinogenic for man (Carcinogenicity category 2) [8]. The HPLC elution program was optimized to obtain the best peak shape and resolution. Insecticides, rodenticides, fungicides, herbicides, anti-sprouting products . Until further testing has been done, it should be treated as a possible teratogen in humans. Pentachlorophenol (PCP) is a chlorinated derivative of phenol with empirical formula C6 Cl 5 OH and molecular weight 266.34. Human data: Dusts are particularly irritating to the eyes and nose at concentrations greater than 1 mg/m 3 but concentrations up to 2.4 mg/m 3 have been tolerated by workers that have been conditioned [Clayton and Clayton 1981]. There are five basic types of chlorophenols (mono- to pentachlorophenol) and 19 different chlorophenols in total when positional isomerism is taken into account. The U.S. EPA has canceled the registration for pentachlorophenol, or "Penta," a wood preservative utilized primarily on utility poles that has been in use for decades. 2017-2019: FOUND FOUND ABOVE HEALTH GUIDELINES FOUND ABOVE LEGAL LIMIT 19 states detected 143 utilities detected 2.5 million people served Health concerns for pentachlorophenol Cancer Short-term exposure to . It is marketed under the trade names, Santophen, Pentachlorol, Chlorophen, Chlon, Dowicide 7, Pentacon, Penwar, Sinituho and Penta among others. Halogenated, sulphonated, nitrated or nitrosated derivatives of phenols or phenol-alcohols. The chemical compound which was first produced in the 1930s has a phenolic smell. Pentachlorophenol is a halogenated hydrocarbon, composed of a benzene ring to which is attached a hydroxide radical making a phenol which is then chlorinated. About half the wood poles in the US are treated with pentachlorophenol, known as "penta" in the trade. Pentachlorophenol (PCP) is an organochlorine compound with a solid white appearance and needle-like crystals. Acute toxicity: Pentachlorophenol is moderately toxic via the oral route, with reported oral LD50 values for various formulations ranging from 27 to 211 mg/kg in rats [69,70]. Name: Pentachlorophenol. Pentachlorophenol (PCP) is a substance whose widespread use, mainly in wood protection and pulp and paper mills, has led to a substantial environmental contamination. They have been detected at low levels in ambient air and . The chemical is banned under the United Nation's Stockholm Convention on Persistent Organic Pollutants, a treaty the US signed but never ratified. Pentachlorophenol occurs in two forms: the anionic phenolate at neutral to alkaline pH; and the undissociated phenol at acidic pH. The molecular weight of pentachlorphenol (C 6 HCl 5 O) is 266.3383. It can be found in two forms: PCP itself or as the sodium salt of PCP, which dissolves easily in water. certified reference material, 5000 g/mL in methanol. First produced in the 1930s, it is marketed under many trade names. It can be found in two forms: PCP itself or as the sodium salt of PCP, which dissolves easily in water. This page contains information on the chemical Pentachlorophenol including: 78 synonyms/identifiers; U.S. Code of Federal Regulations Title 49 Section 172 shipping regulations and proper shipping name; USDOT 2008 Emergency Response Guidebook initial response information. (1) [Note: An oral dose of 401 mg/kg is equivalent to a worker being exposed to about . pentachlorophenol (usually found at hazardous sites) is dark gray to brown and exists as dust, beads, or flakes. Beilstein: 1285380. According to the Environmental Protection Agency, PCP is a possible human carcinogen. Pentachlorophenol can be found in two forms: pentachlorophenol itself or as the sodium salt of Most people can begin to smell pentachlorophenol in water at less than 12 parts pentachlorophenol per million parts of water (ppm). Is pentachlorophenol wood preservative? All Photos (1) CAS Number: 87-86-5. Pentachlorophenol solution. Aldrich-P2604; Pentachlorophenol 0.97; CAS Number: 87-86-5; Linear Formula: C6Cl5OH; find related products, papers, technical documents, MSDS & more at Sigma-Aldrich. What is Pentachlorophenol? [ 1 ] Uses The greatest use of pentachlorophenol is as a wood preservative (fungicide). The presence of such compounds, even at low concentration, can cause unpleasant taste and smell in drinking water . Pentachlorothiophenol | C6HCl5S | CID 8620 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities . PENTACHLOROPHENOL (ISO) 2908.11.00 000. Pentachlorophenol was widely used as a pesticide and wood preservative. The molecular weight of lindane (C 6 H 6 Cl 6) is 290.8314. The molecular basis of the toxic properties of phenoxy herbicides in humans and animals has been insufficiently studied. Select Deselect: Catalog # 31297 Product Name Pentachlorophenol CAS Number 87-86-5 Conc. Pentachlorophenol is an old-line insecticide and wood preservative that is a "reasonably anticipated" human carcinogen and an environmental hazard. Toxicity Profiles RAGs A Format for Pentachlorophenol - CAS Number 87865 .
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